Vladimir mid is slowly getting back this patch 12.17 because of the rise in popularity of mid-lane assassin champions. Vladimir W can easily counter assassins with one shot all in combos. He is a monster during the late game greatly countering assassins as they fall off value as the game progresses.
Best Vladimir Build
Vladimir the Crimson Reaper has a battlemage playstyle, just like in RPG games, he thrives at close combat while casting his spells. He has lots of sustainability and can deal tons of magic damage.
Vladimir W sanguine pool makes him untargetable and when combined with the transcendence rune, he can stay in extended fights for a very long time. Let us first discuss the best runes on Vladimir mid.
Best Vladimir Runes
Vladimir the Crimson Reaper is very strong but he has a very short range, so movement speed is what you need. Nimbus cloak and Phase rush are both runes that will give you a boost in movement speed when fighting enemies.
Best Rune Path
Best Slot 1 (Rune)
Best Slot 2 (Rune)
Best Slot 3 (Rune)
For this Vladimir build Transcendence and Gathering storm will be your best runes when you get past level 11. Gathering Storm will give you more and more ability power raising your overall ability power and HP making you deal more damage and heal stronger.
Transcendence reduces the cooldown of Vladimir's basic abilities which is great because his basic spells are the core spell he needs when fighting multiple enemies. For Inspiration, Cosmic insight along with Magical Footwear will be great for early game sustainability and gold efficiency. These are currently the best Vladimir runes for a Vladimir mid-role.
Best Vladimir Rune Shards
Vladimir players tend to take both adaptive force and the health from the defense as both of these stats increase Vladimir's HP and ability power. You can also use this rune build in the top lane.
Best Rune Shards
+9 Adaptive Force
The cooldown reduction will make you use Vladimir Q transfusion more often giving you incredible sustainability in mid lane.
Best Vladimir Spells
For Vladimir summoner spells, flash, and ghost walk will give him the ability to surprise enemies and keep up with them. These summoner spells are important especially during a team fight for this Vladimir build.
Vladimir players use flash to surprise enemy champions with the burst damage of Vladimir E tides of blood. Vladimir Q transfusion is also great if you activate ghost walk as you can easily kite enemies and just poke them with it. You should also reserve your summoner spells for team fights.
Best Vladimir Abilities Order
Vladimir's main damaging ability is his Q as it has a low cooldown and great sustainability so it will be maxed first in his skill order. It will then be followed by Vladimir E tides of blood in this skill order as this is his nuking ability. It has a really strong burst and great AoE damage.
It is important to know your skill order of Vladimir because if you max E first, you might find it hard to lane against opponents that have faster tempo than you.
Best Vladimir Item
Being a battlemage in league of legends means you need to heal yourself while dealing damage to enemies. Riot games made Vladimir a really hard champion to play but is really strong if you master him. He can build any mythic item and still benefit from it making him deal damage even better.
Best Vladimir Starter items
For his item build you need to start with an item that can give you ability power and help you regenerate faster. The dark seal is an item that can lead to another late-game item making it very gold efficient. It lets Vladimir stack ability power and increases his potion effectiveness for his refillable potion
For better and safer laning however, it depends on the enemy you are facing if you should take a Doran's ring or a Doran's shield. Doran's ring is usually bought first if you are facing an enemy who also has sustain.
Best Vladimir mid game Items
When mid-game comes in league of legends, Vladimir should be strong enough to gank other lanes. Night Harvester makes him really mobile when chasing enemies and Sorcerer's shoes will provide mid-game Magic Penetration.
Rabadon's Deathcap is a great third item for this Vladimir build but this is a situational item that can be replaced with demonic embrace if enemies are too tanky or any other Magic penetration item.
Another alternative item is the hextech rocketbelt as it gives Vladimir more mobility letting him dash forward if the enemy champion has good disengage ability.
Best Final late game Vladimir items
For this Vladimir build you can use your dark seal to turn it into Mejai's soul stealer come late game. Void staff and Shadowflame will complete your item build and these are great late-game items as enemies tend to counter Vladimir by building magic resist items.
Vladimir's passive in league of legends lets him increase his ability power based on his bonus HP and vice versa meaning having high ability power will also make you tanky.
Best Champions to pair Vladimir with
Being a mid lane champion in league of legends means pairing with a jungle ally is great as they can easily gank you wherever they may be. Bel'Veth is a new jungler made by Riot games and is excellent at ganking lanes with no crowd control.
Win Rate %
The same can be said for Rammus and Kindred as all these junglers have excellent gap closers and movement impairing abilities. League of legends also made Vladimir great for team fights as he can use his ultimate ability to increase the damage received by enemies.
Strongest Champions against Vladimir
Swain and Lux easily beats Vladimir in lane because they have much longer range and stronger poke abilities bullying Vladimir out of lane.
Win Rate %
Weakest Champions against Vladimir
These champions are really hard to play and has a slower tempo than Vladimir. He can simply bully these champions out of lane and beat them more during the late game.
Win Rate %
This is the best build for Vladimir this current patch along with the best runes and item build, it might change for the next patch depending on the nerfs on items and buffs that will be imposed by Riot games.