Best Twisted Fate Build Guide | Runes | Spells | Items in League of Legends

Faker has placed Twisted Fate as the most important champion for budding mid-lane mains. So, here are the best Twisted Fate build, runes, spells, items League of Legends can offer him, as well as his greatest counters.
Best Twisted Fate Build
Twisted Fate is a ranged mid-lane champion. However, Twisted Fate mid doesn't play like the usual mages, and his playstyle is that of a playmaker.

Best Twisted Fate Runes
Twisted Fate requires additional help to make his early-game trades hurt. So, the Domination Rune Path offers Electrocute. With Twisted Fate's abilities, it's easy to proc and win every early-game trade with the burst damage.
Best Rune Path | Domination
![]() | Inspiration![]() |
Best Keystone | Electrocute
![]() | |
Best Slot 1 (Rune) | Taste of Blood
![]() | Minion Dematerializer
![]() |
Best Slot 2 (Rune) | Eyeball Collection
![]() | Timewarp Tonic
![]() |
Best Slot 3 (Rune) | Treasure Hunter
![]() |
The Inspiration Rune Tree is useful for better minion wave clears with the Minion Dematerializer, as well as the all-in potential the Timewarp Tonic gives. If only the Gathering Storm rune was here, instead of the Sorcery tree as well. Even so, Inspiration is still more useful.
Best Twisted Fate Rune Shards
When it comes to playing Twisted Fate mid, the worst matchups are those that outrange you, such as the various mages.
Best Rune Shards | Effect |
Offense
![]() | +12% Attack Speed |
Flex
![]() | +9 Adaptive Force |
Defense
![]() | +8 Magic Resist |
So your best bet is the increased attack speed, to proc electrocute faster, as well as Magic Resist so as not to take too much damage in return.
Best Twisted Fate Spells
When it comes to Summoner Spells, there are only a few champions who are managing League of Legends trials, without using Flash. Those are Shaco or Tryndamere. Flash is a must-have when playing Twisted Fate, as Flash is, without a doubt, the best Summoner Spell in the game, overall.
Best Spells | Icon |
Flash | ![]() |
Ignite | ![]() |
Ignite, on the other hand, is the most common secondary Summoner Spell in the enemy champion in the mid-lane. Whether it's to kill the enemy mid lane, or to run down the enemy bot lane, it's also a must-have.

Best Twisted Fate Abilities Order
The first ability to level on Twisted Fate, out of his skill order, is his W - Pick a Card. It's the second ability to be maxed, however. It offers AoE damage, a stun, or mana return to Twisted Fate on his next attack, as the various effects of the cards he picks.
After that, the next ability in his skill order is his E - Stacked Deck. It's the last ability to be leveled on Twisted Fate. Instead, it's used for the bonus damage on his fourth attack, as well as the bonus attack speed.

Finally, besides Twisted Fate's ultimate, we have his Q -Wild Cards. It's the last ability to be leveled but the first to be maxed. Its main usage is as a poking tool in lane, with its magic damage, and as a wave clear tool, with three cards thrown in a straight line from him.
And, as always, Twisted Fate's ultimate is his bread and butter. It's used to gank unsuspecting champions, wherever they may be, as it grants vision of the enemy champions on the map. you can use it to help your jungle, or to gank on the opposite side of where he does it, for maximum map domination.
Best Twisted Fate Items
Twisted Fate does not just stack ability power as most other mid-lane mages do. Instead, his build path is a little different, and all Twisted Fate guides emphasize his peculiar playstyle of high movement speed, and high single-target damage. Whether it's physical damage or magic damage is irrelevant.
Best Starter Twisted Fate Items
Starting off, Twisted Fate buys a Corrupting Potion as his starter item, for all of his started gold. It works perfectly with his auto-attack playstyle, and Timewarp Tonic.
First Item |
Corrupting Potion
![]() |
Best Mid Game Twisted Fate Items
In the mid-game, your core build should be ready, and it consists of Everfrost as his Mythic Item, ionian Boots of Lucidity for the ability haste, and Rapid Firecannon.
First Item | Second Item | Third Item |
Everfrost
![]() | Ionian Boots of Lucidity
![]() | Rapid Firecannon
![]() |

Best Final Late Game Twisted Fate Items
After Twisted Fate finishes his core build, and ganking is no longer that easy to pull off, he can focus on buying the usual full damage ability power items the other mages do.
First Item | Second Item | Third Item | Fourth Item | Fifth Item | Sixth Item |
Everfrost
![]() | Ionian Boots of Lucidity
![]() | Rapid Firecannon
![]() | Zhonya's Hourglass
![]() | Lich Bane
![]() | Mejai's Soulstealer
![]() |
With Twisted Fate's Gold Card, he can easily set up picks on enemy champions, thus earning a lot of Mejai's stacks, while Lich Bane, along with Rapid Firecannon ensures that his first attack hits like a truck. If the enemy has a lot of tenacity, Everfrost is there to keep them in place.
Strongest Champion Against Twisted Fate
The champions Twisted Fate does badly against are those that he can't leave alone in the mid-lane to farm or those that can outright bypass all of the tricks the Card Master has, to kill him directly during the laning phase.
Champion | Win Rate % | Icon |
Vladimir | 25% | ![]() |
Rumble | 25% | ![]() |
Ekko | 30% | ![]() |
Weakest Champion Against Twisted Fate
On the other hand, Twisted Fate does well into champions whose high movement he can easily stop, with his Gold Card, as well as those that can't scale as quickly as he can snowball the game.
Champion | Win Rate % | Icon |
Fizz | 80% | ![]() |
Azir | 71.4% | ![]() |
Ryze | 56.4% | ![]() |
Twisted Fate is the one who dominates the map of Summoner's Rift, and with this, highest win rate Twisted Fate guide, you can as well.