Best Twitch Build Guide | Runes | Spells | Items in League of Legends

Twitch is one of the oldest League of Legends champions, being released 13 years ago by Riot Games, and has become one of their registered trademarks. At least when it comes to annoying champions. These are the best Twitch build, runes, spells, items League of Legends can offer him, as well as his greatest counters.

Best Twitch Build

Twitch is not your typical ADC champion. He deals in poison as well as in physical damage. So, the best Twitch build needs to take advantage of both.

Best Twitch Runes

There are two things the Plague Rat likes to do. Stack attack speed with the best Twitch build and overwhelm his opponents before they can even mount a proper defense. That is exactly what the Precision Tree is for, to give him attack speed in the early game, as well as the late game, with the best runes.

Best Rune Path	Precision	Domination
Best Keystone	Lethal Tempo
Best Slot 1 (Rune)	Presence of Mind	Taste of Blood
Best Slot 2 (Rune)	Legend: Alacrity	Treasure Hunter
Best Slot 2 (Rune)	Coup De Grace

The second favorite pastime of this ADC is to surprise his opponents from an invisible ambush. The Domination tree lets him maximize the profits from these kills, as well as gives him some sustain so he can do it more often.

Best Twitch Rune Shards

Keeping in with his love of Attack speed and cumulative damage from poison, Twitch takes both in his Rune Shards.

Best Rune Shards	Effect
Offense	+10% Attack Speed
Flex	+9 Adaptive Force
Defense	+6 Armor

As Twitch is played in the bottom lane, he will always be up against an enemy ADC. So, the best defensive option for Twitch, in most League of Legends games, is armor.

Best Twitch Spells

When it comes to Summoner Spells, there are only a few champions who are managing League of Legends trials, without using Flash. Those are Shaco or Tryndamere. Flash is a must-have when playing Twitch, as Flash is, without a doubt, the best Summoner Spell in the game, overall.

Best Spells	Icon
Flash
Exhaust

Twitch is an incredibly squishy champion. Even more than the average ADC, so Exhaust is an ability that comes in handy even more for Twitch, in both the early game and the late game.

Best Twitch Abilities Order

The first ability to level on Twitch, out of his skill order, is his E - Contaminate. It serves as the best way to one-shot an enemy, by applying additional damage from your passive upon a target, as well as winning early game trades with the bonus damage.

After that, the next ability in his skill order is his Q - Camouflage, which makes Twitch enter camouflage, as it doesn't grant true invisibility. It grants Twitch Attack Speed as well as allows him to easily get to a good position to flank enemies, and use his ult when getting officially involved in a team fight.

Finally, besides Twitch's ultimate, we have his W - Venom Cask. It's an AoE ability, that marks enemies with Twitch's passive, and allows him for easier stacking of his poison.

And, as always, Twitch's ultimate is his bread and asser. In a team fight, Twitch ADC uses his Spray and Pray, to decimate the enemy team. He just needs someone to hold their attention.

Best Twitch Items

Twitch is the ADC that attacks the entire enemy team at once. So, he needs the items to bring the pain, and use all of his, including the magical damage on his poison, in effect.

Best Twitch Starter Items

As is the case with any Attack Damage Carry, Twitch starts out with the Doran's Blade, for the damage and the omnivamp, and the Health Potions to round out the starting gold.

First Item	Second Item
Doran's Blade	Health Potion

Best Mid Game Twitch Items

In the mid-game, if you’ve played the laning phase correctly, your core build should be ready. It consists of a non-negotiable Kraken Slayer as a Mythic Item, Berserker's Greaves, and Blade of the Ruined King.

First Item	Second Item	Third Item
Blade of the Ruined King	Berserker's Greaves	Kraken Slayer

Interestingly enough, Blade of the Ruined King needs to be bought before Kraken Slayer. Though Mythic Items usually give a better early-game power spike, but in Twitch's case, the effect on Blade of the Ruined King can't be ignored, as he easily stacks the three auto attacks needed.

Best Final Late Game Twitch Items

As we've said before, Twitch is one of the squishiest champions in the game, and defending him can only go so far. So, in his case, the best defense is a good offense.

First Item	Second Item	Third Item	Fourth Item	Fifth Item	Sixth Item
Blade of the Ruined King	Berserker's Greaves	Kraken Slayer	Runaan's Hurricane	Lord Dominik's Regards	Infinity Edge

Runaan's Hurricane synergizes with Twitch's ultimate extremely well, while Lord Dominik's Regards ensures that he can shred through enemy tanks as well as their carries.

Best Champions to Pair Twitch With

Twitch works best with enchanters that can enhance his capabilities in damaging an enemy, while also hindering them from harming him. Or, as is the case with Amumu, those who can set the entire enemy team to Twitch on a silver platter.

Champion	Win Rate %	Icon
Nami	56.8%
Renata Glasc	55.2%
Amumu	54.2%

Strongest Champions Against Twitch

The champions that get up close and personal with Twitch, and can take a 1v1 against him early, either through damage or sustain, are the ones he needs to watch out for.

Champion	Win Rate %	Icon
Nilah	47.1%
Draven	47.1%
Xayah	27.7%

Weakest Champions Against Twitch

On the other hand, the champions that have no way to react to Twitch's sudden ambush, nor a way to out damage him or run away are the ones you like to play Twitch against.

Champion	Win Rate %	Icon
Aphelios	55.1%
Jinx	55%
Sivir	53.5%

It’s these enemies that Twitch likes the most and dealing a killing blow to them is easy enough to do, by following this highest win rate Twitch guide, as well as the other Twitch guides found on our site, such as his best supports.