Best Zoe Build Guide | Runes | Spells | Items in League of Legends

Zoe Mid Lane is busted, but make sure you are playing her correctly, otherwise her potential is wasted. This guide will show make you the best Zoe you can be!

Updated on Mar 05, 2024
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Best Zoe Build Guide | Runes | Spells | Items in League of Legends

Zoe was a menace when she was released, but over the years, the magical thief has been nerfed and changed a lot, so now she is a lot more balanced.

She has a 50.4% Win Rate, a 2.9% Pick Rate, and only a 1.5% Ban Rate, so one-tricking her is possible!

We have the best of the Zoe Support build guides out there for the Riot Games MOBA, with the Zoe runes, the Zoe build, and Zoe’s matchups!

Best Zoe Build


Best Zoe Runes

Zoe’s rune set are the best runes and focuses on Domination and Inspiration!

Best Rune Path



Best Keystone


Best Slot 1 (Rune)

Taste of Blood

Minion Dematerializer

Best Slot 2 (Rune)

Eyeball Collection

Cosmic Insight

Best Slot 3 (Rune)

Treasure Hunter

Electrocute helps Zoe poke from a distance. Taste of Blood heals her when she bursts early game- increased when Eyeball Collection and Treasure Hunter are maxed!

Inspiration gives her Minion Dematerializer, a rune basically only Zoe uses. This means she can kill a balloon minion for her W, Spell Thief passive. Finally, take Cosmic Insight, which gives Zoe +18 Summoner Spell Haste and +10 Item Haste. Time Warp Tonic is a good alternative!

Best Zoe Rune Shards

Best Rune Shards



+10% Attack Speed


+9 Adaptive Force (5.4 AD or 9 AP)


+8 Magic Resist

With Zoe’s main role to poke and burst, extra damage helps, +9 Adaptive Force is incredible from Flex. The extra 10% Attack Speed means she can use her passive more! Magic Resist in Defense is welcome!

Best Zoe Summoner Spells

Best Spells




Hecarim and Shaco are two of the few champions that don’t use Flash, but Zoe needs it to get more distance on her Q, Paddle Star. Ignite is great with her abilities! She doesn’t want defensive spells!


Best Zoe Abilities Order

Level the right abilities at the right time! Here is Zoe’s skill order.


Max Q, Paddle Star! first, and level it first. Second, get E, Sleepy Trouble Bubble, and max it second. This works well with Q, Paddle Star!, the Cooldown decreasing to 12 seconds is great! Finally, get your W, Spell Thief. Zoe’s Ultimate Ability, Portal Jump levels up at 6,12, and 16.

Best Zoe Items

Zoe builds Ability Power items throughout her build.

Best Starter Zoe Items

First Item

Second Item

Doran’s Ring

Two Health Potions

Doran’s Ring keeps Zoe’s mana high with its Drain passive, she farms easier with its Focus passive. The two Health Potions help her recover after a trade.

Best Mid Lane Game Zoe Items

These are the core Zoe items that you want to build!

First Item

Second Item

Third Item

Luden’s Tempest

Sorcerer’s Shoes


Build Lost Chapter first, then Luden’s Tempest as Zoe’s mythic item. Zoe gets small AOE damage and 6 MR, 80 AP, 600 Mana, and 20 Ability Haste. Sorcerer’s Shoes second helps Zoe a lot, but Ionian Boots of Lucidity are also viable!

Shadowflame is your first high-damage item, with 100 Ability Power and 200 HP. It also increases MR too!


Best Final Late Game Zoe Items

This is the final build that you want.

First Item

Second Item

Third Item

Fourth Item

Fifth Item

Sixth Item

Luden’s Tempest

Sorcerer’s Shoes


Zhonya’s Hourglass

Rabadon’s Deathcap

Void Staff

Assassins one-shot Zoe, such as Zed or Talon, but Zoe builds Zhonya’s Hourglass fourth. Zoe is quite weak to CC, the two seconds invulnerability is incredibly useful to stall. It gives 65 AP, 45 Armor, and 10 Ability Haste.

Rabadon’s Deathcap is fifth, with 120 AP a Magic Damage increase of 35%. This is followed by Void Staff, which adds 65 AP and another 40% Magic Penetration.

Best Champions to pair Zoe with

These are the best champions to play with Zoe.


Win Rate %






Master Yi


Strongest Champions against Zoe

These enemy champions are Zoe’s weaknesses!


Win Rate %








Fizz and Kassadin can avoid a lot of her abilities, whereas Lux can poke Zoe from a distance, as well as throw her abilities to where Zoe will portal back to!

Weakest Champions against Zoe

Zoe will smash these three!


Win Rate %








Azir and Vladimir get poked down really easily, as neither can get in range of Zoe, and she can just avoid their abilities. Galio has the same, as he has little gap closing that can outdo Zoe’s Portal Jumping.

Hopefully, you are now ready to climb with Zoe Mid in League of Legends games and demolish any enemy champion now! We also have an article on the best Zoe skins too!

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